Safety and Effectiveness of BNT327, an Investigational Therapy in Combination With Chemotherapy for Patients With Untreated Small-cell Lung Cancer

Trial status:Recruiting
Trial ID:
BNT327-03
NCT ID:
EudraCT ID:
N/A
Sponsor:
The sponsor of a clinical trial is the company, institution or individual that takes responsibility for initiating, managing, and/or financing a clinical investigation. BioNTech collaborates with other pharmaceutical companies or institutions (collaborators) to develop certain new medicines. In particular cases BioNTech's collaborators are leading specific clinical trials and are acting as sponsors accordingly.
BioNTech SE
Recruiting

Trial Details

This is a Phase III, multisite, randomized, double-blinded study to investigate BNT327 combined with chemotherapy (etoposide/carboplatin) compared to atezolizumab combined with chemotherapy (etoposide/carboplatin) for the treatment of participants with previously untreated extensive-stage small-cell lung cancer (ES-SCLC).

Medical Condition
  • Lung Cancer
  • Trial Drug
  • BNT327
  • See more
  • Atezolizumab
  • Etoposide
  • Carboplatin
  • Phase
    Phase 3
    Type
    Interventional
    Estimated Enrolment
    439
    Estimated Trial Date
    Feb 2025 - Apr 2028

    Trial Participant Requirements

    Age
    18+ years
    Sex
    Female & Male
    Healthy Volunteers
    No

    Trial Locations

    Location
    Status
    Location
    Clermont Oncology Center
    Clermont, Florida, United States, 34711
    Status
    Recruiting
    Location
    Fort Wayne Medical Oncology and Hematology, Inc
    Fort Wayne, Indiana, United States, 46804
    Status
    Recruiting
    Location
    Nebraska Hematology-Oncology (NHO)
    Lincoln, Nebraska, United States, 68506
    Status
    Recruiting
    Location
    Millennium Research and Clinical Development, LLC
    Houston, Texas, United States, 77090
    Status
    Recruiting
    Location
    Hematology Oncology Associates of Fredericksburg, Inc.
    Fredericksburg, Virginia, United States, 22408
    Status
    Recruiting