GEN1042 Safety Trial and Anti-tumor Activity in Participants With Malignant Solid Tumors

Trial status:Recruitment Complete
Trial ID:
GCT1042-01
NCT ID:
NCT04083599
EudraCT ID:
2018-003716-47
EU Trial (CTIS) Number:
2023-508526-10
Sponsor:
The sponsor of a clinical trial is the company, institution or individual that takes responsibility for initiating, managing, and/or financing a clinical investigation. BioNTech collaborates with other pharmaceutical companies or institutions (collaborators) to develop certain new medicines. In particular cases BioNTech's collaborators are leading specific clinical trials and are acting as sponsors accordingly.
Genmab
Recruitment Complete

Trial Details

The goal of this trial is to learn about the antibody GEN1042 when it is used alone and when it is used together with another antibody cancer drug, pembrolizumab (with or without chemotherapy), for treatment of participants with certain types of cancer.

Medical Condition
  • Solid Tumors
  • Lung Cancer
  • Colorectal Cancer
  • Skin Cancer
  • Head and Neck Cancer
  • Pancreatic Cancer
    • Trial Drug
  • GEN1042
    • See more
  • Pembrolizumab
  • Cisplatin
  • Carboplatin
  • 5-FU
  • Gemcitabine
  • Nab paclitaxel
  • Pemetrexed
  • Paclitaxel
    • Phase
    Phase 1/Phase 2
    Type
    Interventional
    Estimated Enrolment
    1287
    Estimated Trial Date
    Sep 2019 - Dec 2025

    Trial Participant Requirements

    Age
    18+ years
    Sex
    Female & Male
    Healthy Volunteers
    No

    Trial Locations

    Location
    Status
    Location
    Alaska Oncology and Hematology LLC
    Anchorage, Alaska, United States, 99508
    Status
    Location
    Cancer & Blood Specialty Clinic
    Los Alamitos, California, United States, 90720
    Status
    Location
    Moores Cancer Center at the UC San Diego Health
    San Diego, California, United States, 92037
    Status
    Location
    Yale University Cancer Center
    New Haven, Connecticut, United States, 06520
    Status
    Location
    ChristianaCare
    Newark, Delaware, United States, 19713
    Status
    Location
    Mount Sinai Comprehensive Cancer Center
    Miami Beach, Florida, United States, 33140
    Status
    Go to page