A Study of YL202 in Patients With Locally Advanced or Metastatic Non-small Cell Lung Cancer and Breast Cancer

Trial status:Recruiting
Trial ID:
YL202-INT-101-01
NCT ID:
EudraCT ID:
N/A
Sponsor:
The sponsor of a clinical trial is the company, institution or individual that takes responsibility for initiating, managing, and/or financing a clinical investigation. BioNTech collaborates with other pharmaceutical companies or institutions (collaborators) to develop certain new medicines. In particular cases BioNTech's collaborators are leading specific clinical trials and are acting as sponsors accordingly.
MediLink Therapeutics (Suzhou) Co., Ltd.
Recruiting

Trial Details

This is a phase 1, multicenter, open-label, first-in-human study of YL202 conducted in the United States and China. The study will evaluate the safety and tolerability of YL202 in patients with locally advanced or metastatic epidermal growth factor receptor (EGFR)-mutated NSCLC or hormone receptor (HR)-positive and HER2-negative BC, which have been heavily treated by standard treatment.

Medical Condition
  • Lung Cancer
  • Breast Cancer
  • Trial Drug
  • YL202
  • Phase
    Phase 1
    Type
    Interventional
    Estimated Enrolment
    80
    Estimated Trial Date
    Dec 2022 - Dec 2025

    Trial Participant Requirements

    Age
    18+ years
    Sex
    Female & Male
    Healthy Volunteers
    No

    Trial Locations

    Location
    Status
    Location
    BRCR Global
    Plantation, Florida, United States, 33322
    Status
    Recruiting
    Location
    Karmanos Cancer Institute
    Detroit, Michigan, United States, 48201
    Status
    Recruiting
    Location
    The University of Texas MD Anderson Cancer Center
    Houston, Texas, United States, 77030
    Status
    Recruiting
    Location
    Next Oncology-Dallas
    Irving, Texas, United States, 75039
    Status
    Recruiting
    Location
    UT health east Texas HOPE Cancer Center
    Tyler, Texas, United States, 75701
    Status
    Recruiting
    Location
    Next Oncology-Virginia
    Fairfax, Virginia, United States, 22031
    Status
    Recruiting